C-reactive protein (CRP) is an acute-phase protein that includes a homopentameric construction and Ca-binding specificity for phosphocholine (PCh). Expression of CRP is regulated primarily on the transcriptional degree with interleukin-6 being the principal inducer of the gene in the course of the acute section. The crystal construction of CRP has been decided and the topology and chemical composition of its ligand-binding web site decided. The huge distribution of PCh in polysaccharides of pathogens and in mobile membranes permits CRP to acknowledge a variety of pathogenic targets in addition to membranes of broken and necrotic host cells. CRP sure to a multivalent ligand can effectively provoke the meeting of a C3 convertase by the classical pathway and thus beautify the floor of the ligand with opsonic complement fragments.
However, the protein doesn’t favor the formation of a C5 convertase and subsequently, CRP-initiated complement activation doesn’t mediate acute inflammatory reactions and membrane injury. CRP additionally interacts with Fc receptors on phagocytic cells and acts as an opsonin. Other CRP-initiated alerts by interactions with neutrophil Fc receptors have an total anti-inflammatory impact. Thus, the principle organic operate of CRP seems to be host protection towards bacterial pathogens and clearance of apoptotic and necrotic cells. Protection from deadly bacterial an infection, from complement-induced alveolitis, and from endotoxemia has been confirmed in vivo utilizing transgenic mice.
Additional capabilities, together with participation in atherogenesis and pathogenesis of myocardial damage after myocardial infarction have been reported. However, the burden of the proof is that CRP like different acute-phase proteins is a part first line of innate host protection. Calcium oxalate (CaOx) crystals are distributed amongst all taxonomic ranges of photosynthetic organisms from small algae to angiosperms and big gymnosperms. Accumulation of crystals by these organisms will be substantial. Major capabilities of CaOx crystal formation in crops embrace high-capacity calcium (Ca) regulation and safety towards herbivory.
Ultrastructural and developmental analyses have demonstrated that this biomineralization course of will not be a easy random physical-chemical precipitation of endogenously synthesized oxalic acid and environmentally derived Ca. Instead, crystals are shaped in particular shapes and sizes. Genetic regulation of CaOx formation is indicated by fidelity of crystal morphology inside species, cell specialization, and the outstanding coordination of crystal development and cell growth. Using a wide range of approaches, researchers have begun to unravel the beautiful management mechanisms exerted by cells specialised for CaOx formation that embrace the equipment for uptake and accumulation of Ca, oxalic acid biosynthetic pathways, and regulation of crystal development.
Expression of bitter style receptors of the T2R household within the gastrointestinal tract and enteroendocrine STC-1 cells.
Although a job for the gastric and intestinal mucosa in molecular sensing has been identified for many years, the preliminary molecular recognition occasions that sense the chemical composition of the luminal contents has remained elusive. Here we recognized putative style receptor gene transcripts within the gastrointestinal tract. Our outcomes, utilizing reverse transcriptase-PCR, exhibit the presence of transcripts akin to a number of members of the T2R household of bitter style receptors within the antral and fundic gastric mucosa in addition to within the lining of the duodenum.
In addition, cDNA clones of T2R receptors have been detected in a rat gastric endocrine cell cDNA library, suggesting that these receptors are expressed, no less than partly, in enteroendocrine cells. Accordingly, expression of a number of T2R receptors additionally was present in STC-1 cells, an enteroendocrine cell line. The expression of alpha subunits of G proteins implicated in intracellular style sign transduction, particularly Galpha(gust), and Galpha(t)-(2), additionally was demonstrated within the gastrointestinal mucosa in addition to in STC-1 cells, as revealed by reverse transcriptase-PCR and DNA sequencing, immunohistochemistry, and Western blotting.
Furthermore, addition of compounds extensively utilized in bitter style signaling (e.g., denatonium, phenylthiocarbamide, 6-n-propil-2-thiouracil, and cycloheximide) to STC-1 cells promoted a speedy enhance in intracellular Ca(2+) focus. These outcomes exhibit the expression of bitter style receptors of the T2R household within the mouse and rat gastrointestinal tract. Many excessive threshold, voltage-gated CaCaCa(2+)-sensitive inactivation, its molecular mechanism is known solely in broad define. We now exhibit that Ca(2+)-dependent inactivation transpires by a Ca(2+)-induced shift of channel gating to a low open chance mode, distinguished by a greater than 100-fold discount of entry fee to the open state.
A gating mechanism that explains this shift quantitatively and allows profitable separation of Ca(2+)- and voltage-sensitive types of inactivation is deduced and examined. Finally, each calmodulin activation and channel (de)phosphorylation are excluded as vital signaling occasions underlying Ca(2+)-induced mode shifts, leaving direct binding of Cachemical initiation occasion for inactivation. The program features a neural community educated to establish secondary construction from residue sequence and chemical shifts.
In vivo imaging of C. elegans ASH neurons: mobile response and adaptation to chemical repellents.
ASH sensory neurons are required in Caenorhabditis elegans for a variety of avoidance behaviors in response to chemical repellents, excessive osmotic options and nostril contact. The ASH neurons are subsequently hypothesized to be polymodal nociceptive neurons. To perceive the character of polymodal sensory response and adaptation on the mobile degree, we expressed the calcium indicator protein cameleon in ASH and analyzed intracellular Ca(2+) responses following stimulation with chemical repellents, osmotic shock and nostril contact.
 Anti-Caspase-2/CASP2 Antibody |
|
MBS1751419-5x01mg |
MyBiosource |
5x0.1mg |
EUR 1870 |
 CASP2 Antibody |
|
32995 |
SAB |
100ul |
EUR 439 |
CASP2 Antibody |
|
32995-100ul |
SAB |
100ul |
EUR 302.4 |
CASP2 Antibody |
|
31011-100ul |
SAB |
100ul |
EUR 302.4 |
CASP2 Antibody |
|
31011-50ul |
SAB |
50ul |
EUR 224.4 |
CASP2 Antibody |
|
1-CSB-PA001230 |
Cusabio |
-
Ask for price
-
Ask for price
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Description: A polyclonal antibody against CASP2. Recognizes CASP2 from Human. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000 |
CASP2 Antibody |
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1-CSB-PA004547GA01HU |
Cusabio |
-
Ask for price
-
Ask for price
|
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Description: A polyclonal antibody against CASP2. Recognizes CASP2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB |
CASP2 Antibody |
|
1-CSB-PA004547LA01HU |
Cusabio |
-
Ask for price
-
Ask for price
|
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Description: A polyclonal antibody against CASP2. Recognizes CASP2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:1000-1:2000, IF:1:200-1:500 |
 Casp2 Antibody |
|
CSB-PA004547XA01MO-02mg |
Cusabio |
0.2mg |
Ask for price |
|
|
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Description: Recombinant Mus musculus (Mouse) Casp2 protein |
Casp2 Antibody |
|
CSB-PA004547XA01MO-10mg |
Cusabio |
10mg |
Ask for price |
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Description: Recombinant Mus musculus (Mouse) Casp2 protein |
CASP2 Antibody |
|
CSB-PA880237XA01DOA-02mg |
Cusabio |
0.2mg |
Ask for price |
|
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Description: Recombinant Arabidopsis thaliana CASP2 protein |
CASP2 Antibody |
|
CSB-PA880237XA01DOA-10mg |
Cusabio |
10mg |
Ask for price |
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Description: Recombinant Arabidopsis thaliana CASP2 protein |
CASP2 Antibody |
|
1-CSB-PA198247 |
Cusabio |
-
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-
Ask for price
|
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Description: A polyclonal antibody against CASP2. Recognizes CASP2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:10000, WB:1:1000-1:5000 |
CASP2 Antibody |
|
1-CSB-PA076198 |
Cusabio |
-
Ask for price
-
Ask for price
|
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Description: A polyclonal antibody against CASP2. Recognizes CASP2 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:10000, WB:1:1000-1:2000, IHC:1:100-1:300 |
CASP2 Antibody |
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E031011 |
EnoGene |
100μg/100μl |
EUR 255 |
|
Description: Available in various conjugation types. |
CASP2 Antibody |
|
E310346b |
EnoGene |
200ul |
EUR 275 |
|
Description: Available in various conjugation types. |
CASP2 Antibody |
|
E19-7642-1 |
EnoGene |
50ug/50ul |
EUR 145 |
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Description: Available in various conjugation types. |
CASP2 Antibody |
|
E19-7642-2 |
EnoGene |
100ug/100ul |
EUR 225 |
|
Description: Available in various conjugation types. |
CASP2 Antibody |
|
E92635 |
EnoGene |
100μg |
EUR 255 |
|
Description: Available in various conjugation types. |
CASP2 Antibody |
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MBS2526315-006mL |
MyBiosource |
0.06mL |
EUR 190 |
CASP2 Antibody |
|
MBS2526315-012mL |
MyBiosource |
0.12mL |
EUR 265 |
CASP2 Antibody |
|
MBS2526315-02mL |
MyBiosource |
0.2mL |
EUR 415 |
CASP2 Antibody |
|
MBS2526315-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1835 |
CASP2 Antibody |
|
MBS7121845-005mg |
MyBiosource |
0.05mg |
EUR 150 |
CASP2 Antibody |
|
MBS7121845-01mg |
MyBiosource |
0.1mg |
EUR 190 |
CASP2 Antibody |
|
MBS7121845-5x01mg |
MyBiosource |
5x0.1mg |
EUR 845 |
CASP2 Antibody |
|
MBS7123130-005mL |
MyBiosource |
0.05mL |
EUR 190 |
CASP2 Antibody |
|
MBS7123130-01mL |
MyBiosource |
0.1mL |
EUR 270 |
CASP2 Antibody |
|
MBS7123130-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1205 |
CASP2 Antibody |
|
MBS7123131-005mL |
MyBiosource |
0.05mL |
EUR 190 |
CASP2 Antibody |
|
MBS7123131-01mL |
MyBiosource |
0.1mL |
EUR 270 |
CASP2 Antibody |
|
MBS7123131-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1205 |
CASP2 Antibody |
|
MBS7136637-005mL |
MyBiosource |
0.05mL |
EUR 220 |
CASP2 Antibody |
|
MBS7136637-01mL |
MyBiosource |
0.1mL |
EUR 300 |
CASP2 Antibody |
|
MBS7136637-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1350 |
CASP2 Antibody |
|
MBS7136732-005mL |
MyBiosource |
0.05mL |
EUR 220 |
CASP2 Antibody |
|
MBS7136732-01mL |
MyBiosource |
0.1mL |
EUR 300 |
CASP2 Antibody |
|
MBS7136732-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1350 |
CASP2 Antibody |
|
MBS9610866-005mL |
MyBiosource |
0.05mL |
EUR 245 |
CASP2 Antibody |
|
MBS9610866-01mL |
MyBiosource |
0.1mL |
EUR 305 |
CASP2 Antibody |
|
MBS9610866-02mL |
MyBiosource |
0.2mL |
EUR 365 |
CASP2 Antibody |
|
MBS9610866-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1495 |
CASP2 Antibody |
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MBS9608233-01mL |
MyBiosource |
0.1mL |
EUR 260 |
CASP2 Antibody |
|
MBS9608233-02mL |
MyBiosource |
0.2mL |
EUR 305 |
CASP2 Antibody |
|
MBS9608233-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1220 |
CASP2 Antibody |
|
MBS8502503-01mg |
MyBiosource |
0.1mg |
EUR 325 |
CASP2 Antibody |
|
MBS8502503-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
CASP2 Antibody |
|
MBS8502503-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
CASP2 Antibody |
|
MBS8502503-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
CASP2 Antibody |
|
MBS8502503-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
CASP2 Antibody |
|
MBS8517029-005mg |
MyBiosource |
0.05mg |
EUR 235 |
CASP2 Antibody |
|
MBS8517029-01mg |
MyBiosource |
0.1mg |
EUR 305 |
CASP2 Antibody |
|
MBS8517029-01mLAF405M |
MyBiosource |
0.1mL(AF405M) |
EUR 465 |
CASP2 Antibody |
|
MBS8517029-01mLAF546 |
MyBiosource |
0.1mL(AF546) |
EUR 465 |
CASP2 Antibody |
|
MBS8517029-01mLAF750 |
MyBiosource |
0.1mL(AF750) |
EUR 465 |
CASP2 Antibody |
|
MBS9402299-005mL |
MyBiosource |
0.05mL |
EUR 300 |
CASP2 Antibody |
|
MBS9402299-01mL |
MyBiosource |
0.1mL |
EUR 390 |
CASP2 Antibody |
|
MBS9402299-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1610 |
CASP2 Antibody |
|
MBS9414946-01mL |
MyBiosource |
0.1mL |
EUR 305 |
CASP2 Antibody |
|
MBS9414946-5x01mL |
MyBiosource |
5x0.1mL |
EUR 1230 |
) CASP2 Antibody (Center) |
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E45R31095G-1 |
EnoGene |
100 ul |
EUR 395 |
CASP2 Antibody (Center) |
|
E45R31095G-4 |
EnoGene |
50 ul |
EUR 295 |
CASP2 Antibody (Center) |
|
MBS9204915-008mL |
MyBiosource |
0.08mL |
EUR 210 |
CASP2 Antibody (Center) |
|
MBS9204915-04mL |
MyBiosource |
0.4mL |
EUR 430 |
CASP2 Antibody (Center) |
|
MBS9204915-5x04mL |
MyBiosource |
5x0.4mL |
EUR 1910 |
 Anti-Caspase-2/CASP2 Antibody Picoband™ |
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A02384-1 |
BosterBio |
100ug/vial |
EUR 154 |
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Description: Western blot, 0.1-0.5μg/ml;_x000D_Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml;_x000D_Direct ELISA, 0.1-0.5μg/ml |
Anti-Caspase-2/CASP2 Antibody Picoband™ |
|
PB9368 |
BosterBio |
100ug/vial |
EUR 154 |
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|
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Description: Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat |
 CASP2 Polyclonal Antibody |
|
A57285 |
EpiGentek |
-
Ask for price
-
Ask for price
-
Ask for price
-
Ask for price
|
- 100 µg
- 20 ul
- 50 ul
- 100 ul
|
CASP2 Polyclonal Antibody |
|
A71830 |
EpiGentek |
-
Ask for price
-
Ask for price
|
|
CASP2 Polyclonal Antibody |
|
E-AB-10051-120uL |
Elabscience Biotech |
120uL |
EUR 240 |
|
|
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Description: Unconjugated |
CASP2 Polyclonal Antibody |
|
E-AB-10051-200uL |
Elabscience Biotech |
200uL |
EUR 399 |
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|
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Description: Unconjugated |
CASP2 Polyclonal Antibody |
|
E-AB-10051-20uL |
Elabscience Biotech |
20uL |
EUR 73 |
|
|
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Description: Unconjugated |
CASP2 Polyclonal Antibody |
|
E-AB-10051-60uL |
Elabscience Biotech |
60uL |
EUR 143 |
|
|
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Description: Unconjugated |
CASP2 Polyclonal Antibody |
|
E-AB-13816-120uL |
Elabscience Biotech |
120uL |
EUR 240 |
|
|
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Description: Unconjugated |
CASP2 Polyclonal Antibody |
|
E-AB-13816-200uL |
Elabscience Biotech |
200uL |
EUR 399 |
|
|
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Description: Unconjugated |
CASP2 Polyclonal Antibody |
|
E-AB-13816-20uL |
Elabscience Biotech |
20uL |
EUR 73 |
|
|
|
Description: Unconjugated |
CASP2 Polyclonal Antibody |
|
E-AB-13816-60uL |
Elabscience Biotech |
60uL |
EUR 143 |
|
|
|
Description: Unconjugated |
 CASP2 Conjugated Antibody |
|
C32995 |
SAB |
100ul |
EUR 476.4 |
CASP2 Conjugated Antibody |
|
C31011 |
SAB |
100ul |
EUR 476.4 |
CASP2 Polyclonal Antibody |
|
E95724 |
EnoGene |
100ul |
EUR 225 |
|
Description: Available in various conjugation types. |
 Casp2 Polyclonal Antibody |
|
MBS2541772-002mL |
MyBiosource |
0.02mL |
EUR 130 |
Casp2 Polyclonal Antibody |
|
MBS2541772-006mL |
MyBiosource |
0.06mL |
EUR 175 |
Casp2 Polyclonal Antibody |
|
MBS2541772-012mL |
MyBiosource |
0.12mL |
EUR 255 |
Casp2 Polyclonal Antibody |
|
MBS2541772-02mL |
MyBiosource |
0.2mL |
EUR 380 |
Casp2 Polyclonal Antibody |
|
MBS2541772-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1675 |
CASP2 Polyclonal Antibody |
|
MBS2527766-002mL |
MyBiosource |
0.02mL |
EUR 135 |
CASP2 Polyclonal Antibody |
|
MBS2527766-006mL |
MyBiosource |
0.06mL |
EUR 190 |
CASP2 Polyclonal Antibody |
|
MBS2527766-012mL |
MyBiosource |
0.12mL |
EUR 265 |
CASP2 Polyclonal Antibody |
|
MBS2527766-02mL |
MyBiosource |
0.2mL |
EUR 415 |
CASP2 Polyclonal Antibody |
|
MBS2527766-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1835 |
CASP2 Polyclonal Antibody |
|
MBS2523945-002mL |
MyBiosource |
0.02mL |
EUR 135 |
CASP2 Polyclonal Antibody |
|
MBS2523945-006mL |
MyBiosource |
0.06mL |
EUR 190 |
CASP2 Polyclonal Antibody |
|
MBS2523945-012mL |
MyBiosource |
0.12mL |
EUR 265 |
CASP2 Polyclonal Antibody |
|
MBS2523945-02mL |
MyBiosource |
0.2mL |
EUR 415 |
CASP2 Polyclonal Antibody |
|
MBS2523945-5x02mL |
MyBiosource |
5x0.2mL |
EUR 1835 |
CASP2 Polyclonal Antibody |
|
MBS8578984-01mL |
MyBiosource |
0.1mL |
EUR 305 |
CASP2 Polyclonal Antibody |
|
MBS8578984-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
CASP2 Polyclonal Antibody |
|
MBS8578984-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
CASP2 Polyclonal Antibody |
|
MBS8578984-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
CASP2 Polyclonal Antibody |
|
MBS8578984-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
CASP2 Polyclonal Antibody |
|
MBS9127055-002mL |
MyBiosource |
0.02mL |
EUR 200 |
CASP2 Polyclonal Antibody |
|
MBS9127055-005mL |
MyBiosource |
0.05mL |
EUR 255 |
CASP2 Polyclonal Antibody |
|
MBS9127055-01mL |
MyBiosource |
0.1mL |
EUR 345 |
CASP2 Polyclonal Antibody |
|
MBS9127055-02mL |
MyBiosource |
0.2mL |
EUR 545 |
CASP2 Polyclonal Antibody |
|
MBS9127055-5x02mL |
MyBiosource |
5x0.2mL |
EUR 2265 |
CASP2 Polyclonal Antibody |
|
MBS8527352-01mL |
MyBiosource |
0.1mL |
EUR 325 |
CASP2 Polyclonal Antibody |
|
MBS8527352-01mLAF405L |
MyBiosource |
0.1mL(AF405L) |
EUR 565 |
CASP2 Polyclonal Antibody |
|
MBS8527352-01mLAF405S |
MyBiosource |
0.1mL(AF405S) |
EUR 565 |
CASP2 Polyclonal Antibody |
|
MBS8527352-01mLAF610 |
MyBiosource |
0.1mL(AF610) |
EUR 565 |
CASP2 Polyclonal Antibody |
|
MBS8527352-01mLAF635 |
MyBiosource |
0.1mL(AF635) |
EUR 565 |
CASP2 Conjugated Antibody |
|
MBS9442187-01mLAF350 |
MyBiosource |
0.1mL(AF350) |
EUR 480 |
CASP2 Conjugated Antibody |
|
MBS9442187-01mLAF405 |
MyBiosource |
0.1mL(AF405) |
EUR 480 |
CASP2 Conjugated Antibody |
|
MBS9442187-01mLAF488 |
MyBiosource |
0.1mL(AF488) |
EUR 480 |
CASP2 Conjugated Antibody |
|
MBS9442187-01mLAF555 |
MyBiosource |
0.1mL(AF555) |
EUR 480 |
CASP2 Conjugated Antibody |
|
MBS9442187-01mLBiotin |
MyBiosource |
0.1mL(Biotin) |
EUR 480 |
CASP2 Conjugated Antibody |
|
MBS9444074-01mLAF350 |
MyBiosource |
0.1mL(AF350) |
EUR 480 |
CASP2 Conjugated Antibody |
|
MBS9444074-01mLAF405 |
MyBiosource |
0.1mL(AF405) |
EUR 480 |
CASP2 Conjugated Antibody |
|
MBS9444074-01mLAF488 |
MyBiosource |
0.1mL(AF488) |
EUR 480 |
CASP2 Conjugated Antibody |
|
MBS9444074-01mLAF555 |
MyBiosource |
0.1mL(AF555) |
EUR 480 |
CASP2 Conjugated Antibody |
|
MBS9444074-01mLBiotin |
MyBiosource |
0.1mL(Biotin) |
EUR 480 |
CASP2 Polyclonal Antibody |
|
RD70039A-120uL |
Reddot Biotech |
120μL |
EUR 345 |
|
|
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Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. |
CASP2 Polyclonal Antibody |
|
RD70039A-200uL |
Reddot Biotech |
200μL |
EUR 570 |
|
|
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Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. |
CASP2 Polyclonal Antibody |
|
RD70039A-20uL |
Reddot Biotech |
20μL |
EUR 97.5 |
|
|
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Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. |
CASP2 Polyclonal Antibody |
|
RD70039A-60uL |
Reddot Biotech |
60μL |
EUR 187.5 |
|
|
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Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. |
CASP2 Polyclonal Antibody |
|
RD75014A-120uL |
Reddot Biotech |
120μL |
EUR 360 |
|
|
|
Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
CASP2 Polyclonal Antibody |
|
RD75014A-200uL |
Reddot Biotech |
200μL |
EUR 630 |
|
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Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
CASP2 Polyclonal Antibody |
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RD75014A-20uL |
Reddot Biotech |
20μL |
EUR 109.5 |
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Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
CASP2 Polyclonal Antibody |
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RD75014A-60uL |
Reddot Biotech |
60μL |
EUR 214.5 |
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Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
CASP2 Polyclonal Antibody |
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RD77256A-120uL |
Reddot Biotech |
120μL |
EUR 360 |
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Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
CASP2 Polyclonal Antibody |
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RD77256A-200uL |
Reddot Biotech |
200μL |
EUR 630 |
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Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
CASP2 Polyclonal Antibody |
|
RD77256A-20uL |
Reddot Biotech |
20μL |
EUR 109.5 |
|
|
|
Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
CASP2 Polyclonal Antibody |
|
RD77256A-60uL |
Reddot Biotech |
60μL |
EUR 214.5 |
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Description: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
 Antibody) Caspase 2 (CASP2) Antibody |
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abx027316-400l |
Abbexa |
400 µl |
EUR 518.75 |
Caspase 2 (CASP2) Antibody |
|
abx027316-400ul |
Abbexa |
400 ul |
EUR 627.6 |
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Caspase 2 (CASP2) Antibody |
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abx027316-80l |
Abbexa |
80 µl |
EUR 281.25 |
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Caspase 2 (CASP2) Antibody |
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abx038262-100ug |
Abbexa |
100 ug |
EUR 469.2 |
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Caspase 2 (CASP2) Antibody |
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abx038262-10kU |
Abbexa |
10 kU |
EUR 337.5 |
Caspase 2 (CASP2) Antibody |
|
abx004377-100l |
Abbexa |
100 µl |
EUR 400 |
Caspase 2 (CASP2) Antibody |
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20-abx004377 |
Abbexa |
-
Ask for price
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- 20 ul
- 50 ul
- 100 ul
- 200 ul
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Caspase 2 (CASP2) Antibody |
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abx004377-20l |
Abbexa |
20 µl |
EUR 175 |
Caspase 2 (CASP2) Antibody |
|
abx004377-50l |
Abbexa |
50 µl |
EUR 275 |
Caspase 2 (CASP2) Antibody |
|
abx025485-100ul |
Abbexa |
100 ul |
EUR 627.6 |
|
|
Caspase 2 (CASP2) Antibody |
|
abx213633-100l |
Abbexa |
100 µl |
EUR 250 |
Caspase 2 (CASP2) Antibody |
|
20-abx213633 |
Abbexa |
-
Ask for price
-
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Caspase 2 (CASP2) Antibody |
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abx213638-100l |
Abbexa |
100 µl |
EUR 250 |
Caspase 2 (CASP2) Antibody |
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20-abx213638 |
Abbexa |
-
Ask for price
-
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Caspase 2 (CASP2) Antibody |
|
abx100447-100l |
Abbexa |
100 µl |
EUR 250 |
Caspase 2 (CASP2) Antibody |
|
20-abx100447 |
Abbexa |
-
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-
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-
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-
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-
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- 10 ug
- 50 ug
- 100 ug
- 200 ug
- 1 mg
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Caspase 2 (CASP2) Antibody |
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abx100447-1ml |
Abbexa |
1 ml |
EUR 675 |
Caspase 2 (CASP2) Antibody |
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abx100447-200l |
Abbexa |
200 µl |
EUR 312.5 |
We discovered that a wide range of noxious stimuli evoked sturdy responses in ASH together with quinine, denatonium, detergents, heavy metals, each hyper- and hypo-osmotic shock and nostril contact. We noticed that repeated chemical stimulation led to a reversible discount within the magnitude of the sensory response, indicating that adaptation happens throughout the ASH sensory neuron. A key part of ASH adaptation is GPC-1, a G-protein gamma-subunit expressed particularly in chemosensory neurons. We hypothesize that G-protein gamma-subunit heterogeneity gives a mechanism for repellent-specific adaptation, which might facilitate discrimination of a wide range of repellents by these polymodal sensory neurons.
